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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPRF
All Species:
29.39
Human Site:
Y951
Identified Species:
58.79
UniProt:
P10586
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10586
NP_002831.2
1907
212879
Y951
R
N
G
R
I
I
S
Y
T
V
V
F
R
D
I
Chimpanzee
Pan troglodytes
XP_001173898
1907
212897
Y951
R
N
G
R
I
T
S
Y
T
V
V
F
R
D
I
Rhesus Macaque
Macaca mulatta
XP_001095521
1911
213091
Y955
R
N
G
R
I
V
S
Y
T
V
V
F
R
D
I
Dog
Lupus familis
XP_532613
1906
212009
Y951
R
N
G
R
I
T
N
Y
S
V
V
Y
R
D
I
Cat
Felis silvestris
Mouse
Mus musculus
A2A8L5
1898
211471
Y942
R
N
G
H
I
T
N
Y
T
V
V
Y
R
D
I
Rat
Rattus norvegicus
Q64604
1898
211475
Y942
R
N
G
R
I
T
N
Y
T
V
V
Y
R
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509444
1884
210807
Y932
R
N
G
R
I
T
N
Y
T
V
V
Y
R
D
I
Chicken
Gallus gallus
Q6YI48
1434
161661
V535
S
S
D
P
A
V
N
V
P
G
P
R
R
T
V
Frog
Xenopus laevis
NP_001083850
1896
213050
M941
L
L
T
K
Y
T
L
M
Y
R
D
I
N
L
P
Zebra Danio
Brachydanio rerio
A4IFW2
1909
213435
Y951
R
N
G
R
I
I
H
Y
I
V
V
Y
R
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16621
2029
229038
D946
N
G
I
I
T
R
Y
D
V
Q
F
H
K
K
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9BMN8
2200
246601
A994
G
N
I
T
S
Y
K
A
I
L
S
A
M
D
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
96.2
96.3
N.A.
95.3
95.3
N.A.
85.7
25.5
69
76.7
N.A.
48.4
N.A.
34.2
N.A.
Protein Similarity:
100
99.7
97.5
98
N.A.
97.4
97.3
N.A.
92.2
40.3
82.1
86
N.A.
63.2
N.A.
50.2
N.A.
P-Site Identity:
100
93.3
93.3
73.3
N.A.
73.3
80
N.A.
80
6.6
0
80
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
93.3
100
93.3
N.A.
86.6
93.3
N.A.
93.3
33.3
6.6
86.6
N.A.
13.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
9
0
0
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
9
0
0
9
0
0
75
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
25
0
0
0
% F
% Gly:
9
9
67
0
0
0
0
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
9
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
17
9
67
17
0
0
17
0
0
9
0
0
75
% I
% Lys:
0
0
0
9
0
0
9
0
0
0
0
0
9
9
0
% K
% Leu:
9
9
0
0
0
0
9
0
0
9
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% M
% Asn:
9
75
0
0
0
0
42
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
9
0
9
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
67
0
0
59
0
9
0
0
0
9
0
9
75
0
0
% R
% Ser:
9
9
0
0
9
0
25
0
9
0
9
0
0
0
0
% S
% Thr:
0
0
9
9
9
50
0
0
50
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
17
0
9
9
67
67
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
9
9
67
9
0
0
42
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _